EFFECT OF CONTROLLED SUBSTRATE FEEDING ON BUTYRIC-ACID PRODUCTION BY CLOSTRIDIUM-TYROBUTYRICUM

被引：48

作者：

FAYOLLE, F

MARCHAL, R

BALLERINI, D

机构：

[1] Direction de Recherche 'Biotechnologie et Environnement', Institut Français du Pétrole, Rueil-Malmaison Cédex, 92506

来源：

JOURNAL OF INDUSTRIAL MICROBIOLOGY | 1990年 / 6卷 / 03期

关键词：

Butyrate production optimisation; Fed-batch; Fermentation control; Fermentation selectivity; Wheat flour hydrolysate;

D O I：

10.1007/BF01577693

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Production of butyric acid from wheat flour hydrolysate was studied with Clostridium tyrobutyricum. The mode of substrate supply was found a key parameter for fermentation performance as large improvements were obtained by feeding with a non-limiting supply of substrate. With this procedure, increases in product concentration and productivity but also in selectivity and yield for butyrate were obtained. Substrate feeding controlled by the rate of gas production was found preferable to constant rate feeding for reason of convenience and flexibility. In these conditions, a butyrate concentration of 62.8 gl-1 was obtained with a productivity of 1.25 gl-1 h-1, a selectivity of 91.5% and a yield of 0.45 g per g of glucose. © 1990 Society for Industrial Microbiology.

引用

页码：179 / 183

页数：5

共 8 条

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