MEMBRANE-INCORPORATED IMMUNOGLOBULIN RECEPTORS INCREASE THE ANTIGEN-PRESENTING ABILITY OF B-CELLS

被引：6

作者：

GONTIJO, CM ^{[1
]}

MOLLER, G ^{[1
]}

机构：

[1] FED UNIV MINAS GERAIS,DEPT BIOCHEM & IMMUNOL,BR-30000 BELO HORIZONTE,MG,BRAZIL

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 1991年 / 34卷 / 05期

关键词：

D O I：

10.1111/j.1365-3083.1991.tb01581.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Monoclonal antibodies specific for ovalbumin were conjugated to palmitate and inserted into the membrane of normal spleen B cells. Their presence in the membrane, as well as their ability to bind ovalbumin, was established by immunofluorescence. The so called anti-ovalbumin-'decorated' B cells were tested for their ability to act as antigen-presenting cells for ovalbumin-specific I-A(d)-restricted T-cell hybridomas. It was found that the antibody-decorated B cells presented antigen more efficiently than non-decorated B cells.

引用

页码：577 / 584

页数：8

共 21 条

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