CELL CYCLE-DEPENDENT CHRONIC INFECTION OF HUMAN CYTOMEGALO-VIRUS IN HUMAN OSTEOGENIC-SARCOMA CELLS

被引：12

作者：

FURUKAWA, T

机构：

来源：

JOURNAL OF GENERAL VIROLOGY | 1979年 / 45卷 / OCT期

关键词：

D O I：

10.1099/0022-1317-45-1-81

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Human osteogenic sarcoma cells transformed by murine sarcoma virus (R970) showed restricted growth of human cytomegalovirus (HCMV). Virus was attached to the same extent as in human fibroblasts. HCMV growth was blocked at early stages after virus penetration. Splitting of infected R970 cultures resulted in infection of all cells. In experiments using synchronized R970 cells it was found that factor(s) associated with the S-phase of the cell cycle might be necessary for establishment of the infection.

引用

页码：81 / 88

页数：8

共 24 条

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