COMPUTED-TOMOGRAPHY FROM OPTICAL PROJECTIONS FOR 3-DIMENSIONAL RECONSTRUCTION OF THICK OBJECTS

被引:17
作者
BROWN, CS
BURNS, DH
SPELMAN, FA
NELSON, AC
机构
[1] Center for Bioengineering, University of Washington, Seattle, WA
来源
APPLIED OPTICS | 1992年 / 31卷 / 29期
关键词
OPTICAL TOMOGRAPHY; COMPUTED TOMOGRAPHY; QUANTITATIVE; PROJECTION; COCHLEA;
D O I
10.1364/AO.31.006247
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
An optical tomography system is developed for generating three-dimensional reconstructions of thick objects from projections. The system is useful for studying transparent structures that are 1-10 mm in diameter. Evaluation of the reconstruction system with a test object demonstrates 98% geometric accuracy, 90% accuracy in the detection of boundaries, and 90% accuracy in the measurement of absorbance. Reconstructions are computed from 96 parallel projections spaced evenly within 180-degrees. Accurate alignment of the projections is achieved with a cross-correlation method following data acquisition. Application of the optical tomography reconstruction technique to an intact cochlea permits measurement of internal structures with 16-mum pixels and a diffraction-limited resolution of 24 mum.
引用
收藏
页码:6247 / 6254
页数:8
相关论文
共 17 条
[1]   EXPERIMENTAL OPTICAL FAN BEAM TOMOGRAPHY [J].
BENNETT, KE ;
FARIS, GW ;
BYER, RL .
APPLIED OPTICS, 1984, 23 (16) :2678-2685
[2]  
BOHNE BA, 1972, LARYNGOSCOPE, V82, P1
[3]  
BRACEWELL R, 1965, FOURIER TRANSFORM IT, P194
[4]   INVERSION OF FAN-BEAM SCANS IN RADIO ASTRONOMY [J].
BRACEWELL, RN ;
RIDDLE, AC .
ASTROPHYSICAL JOURNAL, 1967, 150 (2P1) :427-+
[5]   RECONSTRUCTION OF 3 DIMENSIONAL STRUCTURES FROM ELECTRON MICROGRAPHS [J].
DEROSIER, DJ ;
KLUG, A .
NATURE, 1968, 217 (5124) :130-&
[6]   QUANTITATIVE OPTICAL TOMOGRAPHIC IMAGING OF A SUPERSONIC JET [J].
FARIS, GW ;
BYER, RL .
OPTICS LETTERS, 1986, 11 (07) :413-415
[7]   ALGEBRAIC RECONSTRUCTION TECHNIQUES (ART) FOR 3-DIMENSIONAL ELECTRON MICROSCOPY AND X-RAY PHOTOGRAPHY [J].
GORDON, R ;
BENDER, R ;
HERMAN, GT .
JOURNAL OF THEORETICAL BIOLOGY, 1970, 29 (03) :471-&
[8]  
Haq N, 1988, THESIS U WASHINGTON
[9]  
Hesselink L., 1989, HDB FLOW VISUALIZATI
[10]   COMPUTERIZED TRANSVERSE AXIAL SCANNING (TOMOGRAPHY) .1. DESCRIPTION OF SYSTEM [J].
HOUNDFIELD, GN .
BRITISH JOURNAL OF RADIOLOGY, 1973, 46 (552) :1016-1022