A SHORT AND ENANTIOSELECTIVE SYNTHESIS OF (+)-ANATOXIN-A

被引：29

作者：

SOMFAI, P

AHMAN, J

机构：

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(00)92015-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short and enantioselective total synthesis of the neurotoxic alkaloid (+)-Anatoxin-a (1) from the L-pyroglutamic acid derivative 2 is described. The key step involves an intramolecular cyclisation of an N-tosyl iminium ion derived from the corresponding alpha-methoxy sulfonamide.

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页码：3791 / 3794

页数：4

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