PHOTOCHEMOTHERAPY FOR PSORIASIS REMISSION TIMES - PSORALENS AND UV-A AND COMBINED PHOTOCHEMOTHERAPY WITH ANTHRALIN

被引：24

作者：

CRIPPS, DJ

LOWE, NJ

机构：

[1] Department of Dermatology, University of Wisconsin, Madison, Wisconsin

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 1979年 / 4卷 / 04期

关键词：

D O I：

10.1111/j.1365-2230.1979.tb01644.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Oral methoxsalen and long‐wave ultraviolet light (PUVA) was evaluated in 187 psoriatics, with emphasis on remission and recurrence after therapy. The mean number of years psoriasis had been present was 18.3, the mean psoriatic involvement 34.8% the dose at the time of maximum clearance was 11.8 J/cm2, and the mean number of treatments to achieve maximum clearance was 175. Complete clearance was achieved in sixty‐one patients and in this group the average number of treatments to achieve maximum clearance was 16.8, the initial remission times ranged from 4 to 64 weeks, with an average of 21.6 weeks. In patients subsequently retreated, the remission time was only 12.4 weeks (57%), but the mean number of treatments to achieve maximum clearance was reduced (11.4) and patients responded more easily to treatment. Sixteen patients were treated in addition to PUVA, with anthralin in Lassars' paste with clearing achieved between six and fifteen treatments, a mean of 9.5. Combinations of PUVA with other forms of psoriatic treatment may also help to reduce the cumulative PUVA exposures. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：477 / 483

页数：7

共 14 条

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