FOS AND JUN IN RAT CENTRAL AMYGDALOID NUCLEUS AND PARAVENTRICULAR NUCLEUS AFTER STRESS

被引：81

作者：

HONKANIEMI, J ^{[1
]}

KAINU, T ^{[1
]}

CECCATELLI, S ^{[1
]}

RECHARDT, L ^{[1
]}

HOKFELT, T ^{[1
]}

PELTOHUIKKO, M ^{[1
]}

机构：

[1] KAROLINSKA INST,DEPT NEUROBIOL & HISTOL,S-10401 STOCKHOLM 60,SWEDEN

来源：

NEUROREPORT | 1992年 / 3卷 / 10期

关键词：

LIMBIC SYSTEM; HYPOTHALAMUS; BRAIN; MESSENGER RNA; TRANSCRIPTION FACTOR;

D O I：

10.1097/00001756-199210000-00007

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

THE present paper describes the effect of capsaicin-induced stressful stimulus on the expression of immediate early genes (IEGs) c-fos, c-jun, junB and junD in the hypothalamic paraventricular nucleus (PVN) and the central amygdaloid nucleus (ACe) using in situ hybridization. Stress caused an intense expression of c-fos, c-jun and junB especially in the PVN and ACe and also a clear induction of junD was observed in the PVN. This suggests that the PVN and the ACe are two major targets of stress in the brain. The intense expression of the IEGs in the ACe and PVN suggests that stress may affect neurotransmitter gene expression through Fos and Jun proteins in both these nuclei.

引用

页码：849 / 852

页数：4

共 25 条

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