THE REGIONAL DISTRIBUTION OF THYROTROPIN-RELEASING-HORMONE RECEPTOR MESSENGER-RIBONUCLEIC-ACID IN THE BRAIN

被引：13

作者：

KAJI, H ^{[1
]}

TAKAHASHI, Y ^{[1
]}

CHIHARA, K ^{[1
]}

机构：

[1] KOBE UNIV, SCH MED, DEPT MED, DIV 3, KOBE 650, JAPAN

来源：

NEUROSCIENCE LETTERS | 1993年 / 151卷 / 01期

关键词：

TRH RECEPTOR; MESSENGER RNA; RT-PCR; BRAIN; PITUITARY; SEQUENCE; MOUSE;

D O I：

10.1016/0304-3940(93)90051-L

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Messenger ribonucleic acid (mRNA) from mouse brain was reversely transcribed and complementary deoxyribonucleic acid (cDNA) encoding transmembrane domains (TM) 3 through TM6 of the thyrotropin-releasing hormone receptor (TRH-R) could be amplified by polymerase chain reaction (PCR). The partial cDNA of TRH-R was identical to that of the pituitary in size and sequence. The regional distribution of reverse transcription PCR products (partial cDNA of TRH-R) was similar to that of TRH-Rs themselves, except in cerebellum where TRH-R mRNA levels were relatively higher than the levels of TRH-Rs themselves previously reported.

引用

页码：81 / 84

页数：4

共 10 条

[1] BINDING-SITES FOR THYROTROPIN-RELEASING-HORMONE IN SHEEP NUCLEUS ACCUMBENS RESEMBLE PITUITARY RECEPTORS
BURT, DR
TAYLOR, RL
[J]. ENDOCRINOLOGY, 1980, 106 (05) : 1416 - 1423
[2] BURT DR, 1980, SOC NEUR ABSTR, V6, P255
[3] CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P156, DOI 10.1016/0003-2697(87)90021-2
[4] HINKLE PM, 1973, J BIOL CHEM, V248, P6180
[5] JOHNSON WA, 1989, ANN NY ACAD SCI, V553, P137
[6] ATTENUATION OF THYROID-HORMONE ACTION BY 1,25-DIHYDROXYVITAMIN-D3 IN PITUITARY-CELLS
KAJI, H
HINKLE, PM
[J]. ENDOCRINOLOGY, 1989, 124 (02) : 930 - 936
[7] KAJI H, 1988, J BIOL CHEM, V263, P13588
[8] SHARIF NA, 1989, ANN NY ACAD SCI, V553, P147
[9] EXPRESSION CLONING OF A CDNA-ENCODING THE MOUSE PITUITARY THYROTROPIN-RELEASING-HORMONE RECEPTOR
STRAUB, RE
FRECH, GC
JOHO, RH
GERSHENGORN, MC
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (24) : 9514 - 9518
[10] PROPERTIES OF [H-3]-LABELED (3-ME-HIS2)TRH BINDING TO APPARENT TRH RECEPTORS IN THE SHEEP CENTRAL NERVOUS-SYSTEM
TAYLOR, RL
BURT, DR
[J]. BRAIN RESEARCH, 1981, 218 (1-2) : 207 - 217

← 1 →