NUCLEOPHILIC AROMATIC-SUBSTITUTION ON AROMATIC ALDIMINES-PSI

被引：10

作者：

FLIPPIN, LA

CARTER, DS

DUBREE, NJP

机构：

[1] Institute of Organic Chemistry, Syntex Discovery Research, Palo Alto, CA 94304

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 20期

关键词：

NUCLEOPHILIC AROMATIC SUBSTITUTION; AROMATIC ALDIMINES; ORGANOLITHIUM REAGENTS;

D O I：

10.1016/S0040-4039(00)73675-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ortho-methoxy-substituted benzaldimines derived from 3-amino-2,4-dimethylpentane undergo efficient nucleophilic aromatic substitution with typical organolithium reagents. The aldimine products can be hydrolyzed under mild conditions to provide ortho-alkyl or ortho-phenyl benzaldehyde derivatives.

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页码：3255 / 3258

页数：4

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