SYNTHESIS OF 3-SUBSTITUTED 5-ARYLISOXAZOLES FROM ALPHA,BETA-UNSATURATED OXIMES

被引：21

作者：

ALBEROLA, A

BANEZ, JM

CALVO, L

RODRIGUEZ, MTR

SANUDO, MC

机构：

[1] Departamento de Química Orgánica, Universidad de Valladolid, Valladolid

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1993年 / 30卷 / 02期

关键词：

D O I：

10.1002/jhet.5570300231

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 3-substituted 5-arylisoxazoles from oximes of alpha,beta-unsaturated ketones is studied. The formation of the isoxazole derivatives takes place by cyclization of oximes in the presence of iodine and potassium iodide. The presence of isoxazoline is detected. On the basis of the results a plausible mechanism is suggested.

引用

页码：467 / 471

页数：5

共 17 条

[1]

AUWERS KV, 1933, J PRAKT CHEM, V137, P102

[2] THE ADDITION OF SECONDARY AMINES TO SOME ALPHA-BENZAL KETONES [J].