SOLUTION CONFORMATION AND CRYSTAL-STRUCTURE OF METHYL 3,6-DIDEOXY-BETA-D-RIBOHEXOPYRANOSIDE, AN IMMUNODOMINANT SUGAR OF O-ANTIGENS

被引：5

作者：

BIRNBAUM, GI ^{[1
]}

BUNDLE, DR ^{[1
]}

机构：

[1] NATL RES COUNCIL CANADA,DIV BIOL SCI,OTTAWA K1A 0R6,ONTARIO,CANADA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 582卷 / 03期

关键词：

Crystal structure; Immunodominant sugar; Methyldideoxy riboside; NMR; O-antigen; Solution conformation;

D O I：

10.1016/0304-4165(79)90142-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The crystal structure of methyl 3,6-dideoxy-β-d-ribohexopyranoside monohydrate was determined by direct methods. Crystals are monoclinic, space group P21, with cell dimensions a = 9.089(1), b = 7.668(1), c = 6.956(1) A ̊, β = 101.12°. The molecule adopts the 4C1 chair conformation. The same conformation was also found in both aqueous and chloroform solutions. The pyranose ring is only slightly distorted, and the consequences of this observation on antigen structure are discussed. © 1979.

引用

页码：515 / 524

页数：10

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