GUANIDINOETHANESULFONIC ACID INHIBITOR OF GABA UPTAKE IN RAT CORTICAL SYNAPTOSOMES

被引：13

作者：

LI, YP

LOMBARDINI, JB

机构：

[1] TEXAS TECH UNIV,HLTH SCI CTR,DEPT PHARMACOL,LUBBOCK,TX 79430

[2] TEXAS TECH UNIV,HLTH SCI CTR,DEPT OPHTHALMOL & VISUAL SCI,LUBBOCK,TX 79430

来源：

BRAIN RESEARCH | 1990年 / 510卷 / 01期

关键词：

Cerebral cortex; Guanidinoethanesulfonic acid; Rat brain; Taurine; [!sup]3[!/sup]H]γ-Aminobutyric acid uptake;

D O I：

10.1016/0006-8993(90)90742-T

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Guanidinoethanesulfonic acid (GES) and taurine inhibit [3H]GABA uptake in rat cortical synaptosomes. The inhibitory effects of GES are more potent than taurine. These findings may explain the pharmacologic effects of GES in the CNS. © 1990.

引用

页码：147 / 149

页数：3

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