A PERSPECTIVE ON THE ROLE OF QUALITY-OF-LIFE ASSESSMENT IN CLINICAL-TRIALS

被引：37

作者：

POCOCK, SJ

机构：

[1] London School of Hygiene and Tropical Medicine, London

来源：

CONTROLLED CLINICAL TRIALS | 1991年 / 12卷 / 04期

关键词：

OUTCOME MEASURES; QUALITY-OF-LIFE MEASUREMENT; SELECTING MEASURES;

D O I：

10.1016/S0197-2456(05)80029-7

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

This article summarizes some of the methodologic and practical issues relevant to health related quality-of-life (HRQL) assessment in randomized clinical trials. Particular attention is given to 1) the reasons for undertaking HRQL assessment, 2) the types of clinical trials particularly suitable for HRQL assessment, 3) the selection of appropriate HRQL measures, 4) statistical issues in the design and analysis of HRQL studies, and 5) the need to coordinate progress in HRQL studies in clinical research.

引用

页码：S257 / S265

页数：9