STIMULATION OF INTESTINAL CALCIUM-TRANSPORT AND BONE CALCIUM MOBILIZATION BY PROLACTIN IN VITAMIN-D-DEFICIENT RATS

被引：148

作者：

PAHUJA, DN ^{[1
]}

DELUCA, HF ^{[1
]}

机构：

[1] UNIV WISCONSIN, COLL AGR & LIFE SCI, DEPT BIOCHEM, MADISON, WI 53706 USA

来源：

SCIENCE | 1981年 / 214卷 / 4524期

关键词：

D O I：

10.1126/science.7302575

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In vitamin D-deficient rats intestinal Ca transport increased significantly 4 h after an injection of prolactin, reached a maximum after 8 h, and declined to preinjection levels after 24 h. Similarly, in vitamin D-deficient rats fed a diet low in Ca or P prolactin stimulated an increase in serum calcium in both groups and an increase in serum P in the rats fed the diet low in phosphorus. It appears that prolactin affects organs involved in Ca regulation in a manner that is independent of the vitamin D endocrine system.

引用

页码：1038 / 1039

页数：2

共 20 条

[1]

DeLuca H F, 1978, Ann N Y Acad Sci, V307, P356, DOI 10.1111/j.1749-6632.1978.tb41962.x

[2] SENSITIVE, PRECISE, AND CONVENIENT METHOD FOR DETERMINATION OF 1,25-DIHYDROXYVITAMIN-D IN HUMAN-PLASMA [J].

EISMAN, JA ;

HAMSTRA, AJ ;

KREAM, BE ;

DELUCA, HF .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1976, 176 (01) :235-243

[3] DETERMINATION OF 25-HYDROXYVITAMIN D2 AND 25-HYDROXYVITAMIN D3 IN HUMAN-PLASMA USING HIGH-PRESSURE LIQUID-CHROMATOGRAPHY [J].

EISMAN, JA ;

SHEPARD, RM ;

DELUCA, HF .

ANALYTICAL BIOCHEMISTRY, 1977, 80 (01) :298-305

[4] ACTIVE TRANSPORT OF CALCIUM BY INTESTINE - EFFECTS OF HYPOPHYSECTOMY AND GROWTH HORMONE [J].

FINKELSTEIN, JD ;

SCHACHTER, D .

AMERICAN JOURNAL OF PHYSIOLOGY, 1962, 203 (05) :873-&

[5]

FRANTZ AG, 1979, ENDOCRINOLOGY, V1, P153

[6] RESPONSE OF INTESTINAL CALCIUM-TRANSPORT AND BONE CALCIUM MOBILIZATION TO 1,25-DIHYDROXYVITAMIN D3 IN THYROPARATHYROIDECTOMIZED RATS [J].

GARABEDIAN, M ;

TANAKA, Y ;

HOLICK, MF ;

DELUCA, HF .

ENDOCRINOLOGY, 1974, 94 (04) :1022-1027

[7] INTESTINAL CALCIUM-TRANSPORT - EVIDENCE FOR 2 DISTINCT MECHANISMS OF ACTION OF 1,25-DIHYDROXYVITAMIN-D3 [J].

HALLORAN, BP ;

DELUCA, HF .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1981, 208 (02) :477-486

[8] CALCIUM-TRANSPORT IN SMALL-INTESTINE DURING PREGNANCY AND LACTATION [J].

HALLORAN, BP ;

DELUCA, HF .

AMERICAN JOURNAL OF PHYSIOLOGY, 1980, 239 (01) :E64-E68

[9] SKELETAL CHANGES DURING PREGNANCY AND LACTATION - THE ROLE OF VITAMIN-D [J].

HALLORAN, BP ;

DELUCA, HF .

ENDOCRINOLOGY, 1980, 107 (06) :1923-1929

[10] VITAMIN-D DEFICIENCY AND REPRODUCTION IN RATS [J].

HALLORAN, BP ;

DELUCA, HF .

SCIENCE, 1979, 204 (4388) :73-74

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