LUNG MORPHOMETRY - A NEW-GENERATION OF TOOLS AND EXPERIMENTS FOR ORGAN, TISSUE, CELL, AND MOLECULAR-BIOLOGY

被引:208
作者
BOLENDER, RP
HYDE, DM
DEHOFF, RT
机构
[1] UNIV CALIF DAVIS,DEPT VET ANAT & CELL BIOL,DAVIS,CA 95616
[2] UNIV FLORIDA,DEPT MAT SCI & ENGN,GAINESVILLE,FL 32611
来源
AMERICAN JOURNAL OF PHYSIOLOGY | 1993年 / 265卷 / 06期
关键词
STEREOLOGY; MORPHOMETRY; METHODOLOGY; DESIGN-BASED METHODS; CRITICAL DATA; LUNG; IMMUNOCYTOCHEMISTRY; IN-SITU HYBRIDIZATION; CELL CULTURE; ORGAN CULTURE; CANCER; VASCULAR INJURY;
D O I
10.1152/ajplung.1993.265.6.L521
中图分类号
Q4 [生理学];
学科分类号
071003 [生理学];
摘要
Today all structural information of the lung can be quantified and interpreted in the three-dimensional space of real-world biology. Remarkable achievements in the theory and practice of biological stereology are creating a new generation of data suitable for constructing structural hierarchies. Such hierarchies serve to organize and link biological data, thereby providing a framework on which to build new information systems. In this review, we describe the new tools of quantitative morphology and show how they can be used to design new experiments for lung research.
引用
收藏
页码:L521 / L548
页数:28
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