LEGIONELLA-PNEUMONIA IN TRANSPLANT RECIPIENTS - A CLUSTER OF CASES OF 8 YEARS DURATION

被引:26
作者
PRODINGER, WM
BONATTI, H
ALLERBERGER, F
WEWALKA, G
HARRISON, TG
AICHBERGER, C
DIERICH, MP
MARGREITER, R
TIEFENBRUNNER, F
机构
[1] UNIV HOSP INNSBRUCK, DEPT SURG 1, TRANSPLANTAT UNIT, A-6020 INNSBRUCK, AUSTRIA
[2] CENT PUBL HLTH LAB, PHLS, LEGIONELLA REFERENCE UNIT, LONDON NW9 5HT, ENGLAND
[3] FED PUBL HLTH LAB, A-1096 VIENNA, AUSTRIA
关键词
LEGIONELLA-PNEUMOPHILA; BACTERIAL STRAIN TYPING; ENVIRONMENTAL MONITORING; TRANSPLANTATION; WATER SUPPLY;
D O I
10.1016/0195-6701(94)90042-6
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Infection with Legionella is often encountered in immunosuppressed patients, especially in recipients of renal allografts. From January 1985 until April 1993 14 cases of nosocomial legionella pneumonia were diagnosed (four by culture, 10 by serological methods) on the surgical transplantation unit of Innsbruck University Hospital. All isolates from patients and from the building's hot water were found to be Legionella pneumophila serogroup 1. They were indistinguishable from each other by monoclonal antibody subtyping and restriction fragment length polymorphism pattern and thus indicated a series of infections originating from the same source during a period of more than 8 years. Repeated efforts to control Legionella by raising the temperature in the hot water lines failed to bring permanent success. Replacing the central hot water supply with small electric water heaters installed in the patient rooms on the transplant ward now seems to have reduced the incidence of legionellosis on this unit. However, further infections occurring in transplant patients in other surgical departments in the same building indicate that a major renovation of the whole surgical building's hot water system is necessary. © 1994.
引用
收藏
页码:191 / 202
页数:12
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