SYNTHESIS OF PYRROLIDINES AND PIPERIDINES VIA PALLADIUM-CATALYZED COUPLING OF VINYLIC HALIDES AND OLEFINIC SULFONAMIDES

被引：61

作者：

LAROCK, RC ^{[1
]}

YANG, H ^{[1
]}

WEINREB, SM ^{[1
]}

HERR, RJ ^{[1
]}

机构：

[1] PENN STATE UNIV,DEPT CHEM,UNIVERSITY PK,PA 16802

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 15期

关键词：

D O I：

10.1021/jo00094a031

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The palladium-catalyzed coupling of vinylic halides and olefinic sulfonamides affords good yields of 2-(1-alkenyl)pyrrolidine and -piperidine sulfonamides via vinylpalladium addition to the olefin, regioselective rearrangement to a pi-allylpalladium intermediate, and subsequent intramolecular nucleophilic displacement of palladium.

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收藏

页码：4172 / 4178

页数：7

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