CHOLESTEROL-BIOSYNTHESIS AND PROGESTERONE PRODUCTION BY CHORIONIC CELLS OF THE EARLY SHEEP CONCEPTUS INVITRO

被引：13

作者：

MARCUS, GJ

AINSWORTH, L

LUCIS, R

机构：

[1] Animal Research Institute, Agriculture Canada Ottawa

来源：

STEROIDS | 1979年 / 34卷 / 03期

关键词：

D O I：

10.1016/0039-128X(79)90081-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dissociated trophoblast cells from the chorion of the 21-day sheep conceptus were shown to produce progesterone in vitro. Evidence that this represented synthesis de novo was provided by the prolonged production of progesterone in the absence of added precursor steroids. Radioactive cholesterol was isolated after incubation of dispersed chorionic cells with acetate-1-14C. © 1979.

引用

页码：295 / 303

页数：9

共 23 条

[1] STEROID HORMONE TRANSFORMATIONS BY ENDOCRINE ORGANS FROM PREGNANT MAMMALS .2. FORMAION AND METABOLISM OF PROGESTERONE BY BOVINE AND SHEEP PLACENTAL PREPARATIONS IN VITRO [J].