The recent origins of introns

被引：230

作者：

Palmer, Jeffrey D. ^{[1
]}

Logsdon, John M., Jr. ^{[1
]}

机构：

[1] Indiana Univ, Dept Biol, Bloomington, IN 47405 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1991年 / 1卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-437X(05)80194-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Accumulating evidence that introns are highly restricted in their phylogenetic distribution strongly supports the view that introns were inserted late in eukaryotic evolution into preformed genes and, hence, that exon-shuffling played no role in the assembly of primordial genes. Potential mechanisms of intron insertion and the possible evolution of nuclear introns and their splicing machinery from self-splicing group II introns are also discussed.

引用

页码：470 / 477

页数：8

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