SYNTHESIS, PROPERTIES AND USE OF NITRIDOTRICARBONIC ACID TRI-TERT-BUTYL ESTER

被引：13

作者：

DEGERBECK, F

GREHN, L

RAGNARSSON, U

机构：

来源：

ACTA CHEMICA SCANDINAVICA | 1993年 / 47卷 / 09期

关键词：

D O I：

10.3891/acta.chem.scand.47-0896

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Exhaustive tert-butoxycarbonylation of Boc2NH with Boc2O-DMAP furnishes Boc3N in nearly quantitative yield. This stable compound is susceptible to nucleophiles and affords Boc2NH upon aminolysis. The properties of Boc3N have been exploited in a practical one-pot procedure for the synthesis of Boc2NH from NH4Cl, which is particularly economical in the preparation of (Boc2NH)-N-15.

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页码：896 / 898

页数：3

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