OPTIC-NERVE HEAD BLOOD-FLOW USING A LASER-DOPPLER VELOCIMETER AND HEMORHEOLOGY IN PRIMARY OPEN-ANGLE GLAUCOMA AND NORMAL-PRESSURE GLAUCOMA

被引:122
作者
HAMARD, P [1 ]
HAMARD, H [1 ]
DUFAUX, J [1 ]
QUESNOT, S [1 ]
机构
[1] UNIV PARIS 07,LBHP,CNRS,URA 343,F-75005 PARIS,FRANCE
关键词
D O I
10.1136/bjo.78.6.449
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Optic disc blood how velocity was measured in healthy patients, those with primary open angle glaucoma (POAG), and patients with normal pressure glaucoma (NPG). The velocity of the red blood cells (RBCs) in the capillaries of the optic nerve head (ONH) has been measured with a laser Doppler velocimeter (LDV), and blood viscosity has been evaluated notably by determining the aggregability of the RBCs with an erythroaggregameter. Our results in POAG patients and NPG patients showed that their optic nerve blood how velocity was reduced and that the aggregability of the RBCs was increased. The hyperaggregability of the erythrocytes is responsible for the increase of the local viscosity in the papillary capillary network. These haemodynamic modifications observed in patients with glaucoma support the hypothesis of a vasogenic mechanism that could impair the optic nerve in glaucoma patients.
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页码:449 / 453
页数:5
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