SUBSTRATE-SPECIFICITY OF BLEOMYCIN HYDROLASE

被引：15

作者：

SEBTI, SM

DELEON, JC

MA, LT

HECHT, SM

LAZO, JS

机构：

[1] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510

[2] UNIV VIRGINIA,DEPT CHEM,CHARLOTTESVILLE,VA 22901

[3] UNIV VIRGINIA,DEPT BIOL,CHARLOTTESVILLE,VA 22901

来源：

BIOCHEMICAL PHARMACOLOGY | 1989年 / 38卷 / 01期

关键词：

D O I：

10.1016/0006-2952(89)90160-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：141 / 147

页数：7

共 18 条

[1] BLEOMYCIN-RESISTANT CELLS CONTAIN INCREASED BLEOMYCIN-HYDROLASE ACTIVITIES [J].

AKIYAMA, S ;

IKEZAKI, K ;

KURAMOCHI, H ;

TAKAHASHI, K ;

KUWANO, M .

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[2] ISOLATION AND PRELIMINARY CHARACTERIZATION OF BLEOMYCIN-RESISTANT MUTANTS FROM CHINESE-HAMSTER OVARY CELLS [J].

AKIYAMA, SI ;

KUWANO, M .

JOURNAL OF CELLULAR PHYSIOLOGY, 1981, 107 (01) :147-153

[3] A SEMIAUTOMATED MICROCULTURE METHOD FOR INVESTIGATING GROWTH INHIBITORY EFFECTS OF CYTO-TOXIC COMPOUNDS ON EXPONENTIALLY GROWING CARCINOMA-CELLS [J].

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BAGULEY, BC ;

WILSON, WR .

ANALYTICAL BIOCHEMISTRY, 1984, 139 (02) :272-277

[4] SINGLE-STRAND AND DOUBLE-STRAND DEOXYRIBONUCLEIC-ACID BREAKS PRODUCED BY SEVERAL BLEOMYCIN ANALOGS [J].

HUANG, CH ;

MIRABELLI, CK ;

JAN, Y ;

CROOKE, ST .

BIOCHEMISTRY, 1981, 20 (02) :233-238

[5]

LAZO JS, 1986, CANCER RES, V46, P2236

[6]

LAZO JS, 1984, J PHARMACOL EXP THER, V228, P13

[7] LACK OF METABOLISM AS THE BIOCHEMICAL BASIS OF BLEOMYCIN-INDUCED PULMONARY TOXICITY [J].

LAZO, JS ;

HUMPHREYS, CJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (10) :3064-3068

[8]

LAZO JS, 1987, METABOLISM ACTION AN, P194

[9] PURIFICATION OF BLEOMYCIN HYDROLASE WITH A MONOCLONAL-ANTIBODY AND ITS CHARACTERIZATION [J].

NISHIMURA, C ;

TANAKA, N ;

SUZUKI, H ;

TANAKA, N .

BIOCHEMISTRY, 1987, 26 (06) :1574-1578

[10] SEPARATION OF THE PROTECTIVE ENZYME BLEOMYCIN HYDROLASE FROM RABBIT PULMONARY AMINOPEPTIDASES [J].

SEBTI, SM ;

LAZO, JS .

BIOCHEMISTRY, 1987, 26 (02) :432-437

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