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CLONED FRAGMENTS OF THE PLASMID COLV,I-K94 SPECIFYING VIRULENCE AND SERUM RESISTANCE

被引：183
作者：
BINNS, MM
DAVIES, DL
HARDY, KG
机构：
[1] Biological Laboratory, University of Kent at Canterbury, Canterbury
来源：
NATURE | 1979年 / 279卷 / 5716期
关键词：
D O I：
10.1038/279778a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A cloned BamH1-generated fragment of ColV,I-K94 increased the virulence of Escherichia coli, causing an approximately 100-fold reduction in LD50 for chicks. A genetic determinant f or resistance to the bactericidal effects of serum was mapped to a 5,300 base-pair sequence within the fragment. Neither colicin V nor immunity to colicin V affected the pathogenicity of E. coli for chicks. © 1979 Nature Publishing Group.
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页码：778 / 781
页数：4
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