IS SURGERY NECESSARY IN THE TREATMENT OF PRIMARY GASTRIC NON-HODGKIN LYMPHOMA

被引:36
作者
AVILES, A [1 ]
DIAZMAQUEO, JC [1 ]
DELATORRE, A [1 ]
RODRIGUEZ, L [1 ]
GUZMAN, R [1 ]
TALAVERA, A [1 ]
GARCIA, EL [1 ]
机构
[1] INST MEXICANO SEGURO SOCIAL,CTR MED NACL,HOSP ONCOL,DEPT HEMATOL,MEXICO CITY 73,DF,MEXICO
关键词
LYMPHOMA; MALIGNANT; TREATMENT; NON-HODGKIN LYMPHOMA;
D O I
10.3109/10428199109067630
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Fifty-two patients with primary gastric lymphoma were randomly assigned to two different surgical approaches. Twenty-eight cases were diagnosed by endoscopy and treated with chemotherapy CHOP-Bleo (cyclophosphamide, adriamycin, vincristine, prednisone and bleomycin) alternating with CMED (cyclophosphamide, metothexate, etoposide and dexamethasone). Twenty four cases underwent debulking surgery (partial or total gastrectomy) followed by the same chemotherapy. No differences were observed in relapse free disease or survival in resected or unresected patients. Complications were more frequent and severe in patients who underwent surgery. We believe that surgery is not necessary in the treatment of patients with primary gastric lymphoma. © 1991 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
收藏
页码:365 / 369
页数:5
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