LIFE-THREATENING VENTRICULAR ARRHYTHMIA (TORSADES-DE-POINTES) AFTER HALOPERIDOL OVERDOSE

被引:48
作者
HENDERSON, RA
LANE, S
HENRY, JA
机构
[1] Guy's Hospital, London SE1 9RT, St. Thomas Street
来源
HUMAN & EXPERIMENTAL TOXICOLOGY | 1991年 / 10卷 / 01期
关键词
D O I
10.1177/096032719101000110
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
A 48-year-old woman developed QT prolongation and episodes of life-threatening ventricular tachycardia (torsades de pointes) after intentional overdose of haloperidol and orphenadrine. The arrhythmia did not respond to conventional anti-arrhythmic therapy but was suppressed by atrial overdrive pacing. A literature review identified haloperidol as the most likely cause of the torsades de pointes.
引用
收藏
页码:59 / 62
页数:4
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