SYNTHESIS OF THE ENANTIOMERS OF FELODIPINE AND DETERMINATION OF THEIR ABSOLUTE-CONFIGURATION

被引：26

作者：

LAMM, B ^{[1
]}

SIMONSSON, R ^{[1
]}

SUNDELL, S ^{[1
]}

机构：

[1] UNIV GOTEBORG,FAC MED,DEPT STRUCT CHEM,S-40030 GOTHENBURG,SWEDEN

来源：

TETRAHEDRON LETTERS | 1989年 / 30卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(01)93912-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：6423 / 6426

页数：4

共 6 条

[1] LONG-ACTING DIHYDROPYRIDINE CALCIUM-ANTAGONISTS .1. 2-ALKOXYMETHYL DERIVATIVES INCORPORATING BASIC SUBSTITUENTS [J].

ARROWSMITH, JE ;

CAMPBELL, SF ;

CROSS, PE ;

STUBBS, JK ;

BURGES, RA ;

GARDINER, DG ;

BLACKBURN, KJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (09) :1696-1702

[2] ENANTIOSELECTIVE HANTZSCH DIHYDROPYRIDINE SYNTHESIS VIA METALATED CHIRAL ALKYL ACETOACETATE HYDRAZONES [J].

ENDERS, D ;

MULLER, S ;

DEMIR, AS .

TETRAHEDRON LETTERS, 1988, 29 (49) :6437-6440

[3]

HARDY PM, 1968, TETRAHEDRON LETT, V9, P2525

[4] AN ASYMMETRIC-SYNTHESIS OF CHIRAL NIFEDIPINE ANALOGS [J].

MEYERS, AI ;

OPPENLAENDER, T .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (12) :920-921

[5]

REICH HJ, 1978, SYNTHESIS-STUTTGART, P299

[6] FELODIPINE - A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC USE IN HYPERTENSION [J].

SALTIEL, E ;

ELLRODT, AG ;

MONK, JP ;

LANGLEY, MS .

DRUGS, 1988, 36 (04) :387-428

← 1 →