SUBSTANTIA-NIGRA RETICULATA NEURONS DURING SLEEP WAKING STATES - RELATION WITH PONTOGENICULOOCCIPITAL WAVES

被引：47

作者：

DATTA, S ^{[1
]}

DOSSI, RC ^{[1
]}

PARE, D ^{[1
]}

OAKSON, G ^{[1
]}

STERIADE, M ^{[1
]}

机构：

[1] UNIV LAVAL,FAC MED,DEPT PHYSIOL,NEUROPHYSIOL LAB,QUEBEC CITY G1K 7P4,QUEBEC,CANADA

来源：

BRAIN RESEARCH | 1991年 / 566卷 / 1-2期

基金：

英国医学研究理事会;

关键词：

SUBSTANTIA-NIGRA RETICULATA; PONTOGENICULOOCCIPITAL WAVE; SLEEP WAKING STATE; PERIBRACHIAL AREA;

D O I：

10.1016/0006-8993(91)91723-E

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We have previously hypothesized that the spike bursts of brainstem peribrachial (PB) neurons, leading to ponto-geniculo-occipital (PGO) waves in thalamocortical systems, are triggered by phasic hyperpolarizations of sufficient magnitude or by excitatory inputs reaching a steadily hyperpolarized membrane. We have proposed that the source of these hyperpolarizing actions are substantia nigra pars reticulata (SNr) cells that project to, and exert inhibitory effects upon, PB neurons. Here we tested this hypothesis by recording antidromically identified SNr-PB cells in chronically implanted, naturally sleeping cats. A subpopulation of SNr-PB cells exhibited tonically increased firing preceding by 70-200 ms the thalamic PGO wave. These data support the hypothesis that an enhancement in SNr-cells' discharges may lead to hyperpolarization of PB neurons, with the consequence of spike bursts in one class of PGO-related PB-thalamic neurons.

引用

页码：344 / 347

页数：4

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