THE ABSOLUTE-CONFIGURATION OF AN INTERMEDIATE IN THE ASYMMETRIC-SYNTHESIS OF UNUSUAL AMINO-ACIDS

被引：3

作者：

DHARANIPRAGADA, R ^{[1
]}

BRUCK, M ^{[1
]}

HRUBY, VJ ^{[1
]}

机构：

[1] UNIV ARIZONA,DEPT CHEM,TUCSON,AZ 85721

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1992年 / 48卷

关键词：

D O I：

10.1107/S0108270191013884

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(4R)-3-[(2'R,3'R)-2'-Bromo-3'-(phenylbuta-noyl)]-4-(phenylmethyl)-2-oxazolidinone, C20H20BrNO3, M(r) = 402.30, monoclinic, P2(1), a = 11.542 (2), b = 7.625 (1), c = 11.667 (1) angstrom, beta = 113.97 (1)-degrees, V = 938.2 (2) angstrom3, Z = 2, D(x) = 1.42 g cm-3, lambda(Mo K-alpha) = 0.71073 angstrom, mu= 21.8 cm-1, F(000) = 412, T = 296 +/- 1 K, final R = 0.028 for 2369 observed reflections. Since a D-chiral auxiliary was used the configuration at the alpha-carbon was R as expected. The two carbonyls are aligned in opposite directions to each other to overcome van der Waals repulsions.

引用

页码：1239 / 1241

页数：3

共 13 条

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