CYCLOADDITIONS .48. NOVEL HETEROCYCLES BY BIS HETEROANNULATION OF OXAZOLES

被引：15

作者：

HASSNER, A

FISCHER, B

机构：

[1] Department of Chemistry, Bar-Ilan University

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 10期

关键词：

D O I：

10.1021/jo00010a044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report the first examples of intramolecular Diels-Alder addition of heterodienophiles N = N, C =N, C = O, C = S to oxazoles. The required 5-ethoxy- and 5-phenyloxazoles were synthesized bearing a side chain of variable length on C-2 to which the different heterodienophiles are attached. The products of the thermal bis heteroannulation are 3-triazolines, imidazolines, oxazolines, or thiazolines fused to a five- to six-membered ring. Relative reactivities were established and the mechanism is discussed.

引用

页码：3419 / 3425

页数：7

共 19 条

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