SYNTHESIS OF BRANCHED NUCLEOSIDES CLOSELY RELATED TO AZT, INVOLVING SN2' OPENING OF ANHYDRONUCLEOSIDES

被引：6

作者：

CZERNECKI, S

EZZITOUNI, A

机构：

[1] Laboratoire de Chimie des Glucides, Université Pierre et Marie Curie, 75005 Paris

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 02期

关键词：

D O I：

10.1016/S0040-4039(00)60576-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three 2',3'-unsaturated pyrimidine nucleosides, bearing an azido-methyl group at 2' or 3' were synthesized as potential anti-HIV agents. The key step involves an SN2' opening of 2,2' or 2,3'-anhydronucleosides by azide ion.

引用

页码：315 / 318

页数：4

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