EFFECT OF NASAL ANESTHESIA ON LACRIMAL FUNCTION AFTER NASAL ALLERGEN CHALLENGE

被引：8

作者：

LOTH, S ^{[1
]}

BENDE, M ^{[1
]}

机构：

[1] CENT HOSP SKOVDE,DEPT OTORHINOLARYNGOL,S-54185 SKOVDE,SWEDEN

来源：

CLINICAL AND EXPERIMENTAL ALLERGY | 1994年 / 24卷 / 04期

关键词：

D O I：

10.1111/j.1365-2222.1994.tb00249.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Ocular symptoms in allergic rhinoconjunctivitis arise partly from direct contact of the allergen with the conjunctiva and presumably partly from a naso-lacrimal reflex. The aim was to study the importance of this reflex in allergic rhinitis after topical anaesthesia of the nose. Ten patients with allergic rhinoconjunctivitis to birch pollen were challenged with increasing intranasal doses of allergen until allergic symptoms occurred. The same dose of allergen was used in two other provocations, when the nasal cavity was anaesthetized with topical lidocaine in a double-blind randomized cross-over manner. The effect on the eyes was evaluated by Shirmer's test, a routine method for measuring tear production. Lidocaine per se and/or allergen challenge had no significant effect on tear production. The naso-lacrimal reflex was not involved in the eye symptoms in allergic conjunctivitis.

引用

页码：375 / 376

页数：2