STUDIES ON XANTHURENIC ACID-INSULIN COMPLEX .I. PREPARATION AND PROPERTIES

被引：23

作者：

MURAKAMI, E

机构：

[1] Department of Chemistry, Aichi University of Education, Nagoya Branch, Nagoya

来源：

JOURNAL OF BIOCHEMISTRY | 1968年 / 63卷 / 05期

关键词：

D O I：

10.1093/oxfordjournals.jbchem.a128815

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Xanthurenic acid(XA) and insulin readly combine on simple mixing of their solutions.2. The complex shows a new absorption maximum at 327.5 mμ and this maximum is the same in position as that of a chelate compound of XA, zinc and histidine.3. There are two moles of XA per dimer of insulin in the complex, so that the XA molecule probably combines with the imidazole group of a histidine residue of insulin via a zinc atom.4. The specificity of the binding of XA to protein was studied. © 1968 by the Journal of Biochemistry.

引用

页码：573 / &

共 11 条

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