N-(PHTHALIMIDOALKYL) DERIVATIVES OF SEROTONERGIC AGENTS - A COMMON INTERACTION AT 5-HT1A SEROTONIN BINDING-SITES

被引：55

作者：

GLENNON, RA ^{[1
]}

NAIMAN, NA ^{[1
]}

PIERSON, ME ^{[1
]}

SMITH, JD ^{[1
]}

ISMAIEL, AM ^{[1
]}

TITELER, M ^{[1
]}

LYON, RA ^{[1
]}

机构：

[1] UNION UNIV ALBANY MED COLL,DEPT PHARMACOL,ALBANY,NY 12208

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 08期

关键词：

D O I：

10.1021/jm00128a039

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1921 / 1926

页数：6

共 22 条

[1] POLYCYCLIC ARYLPIPERAZINYL AND HETEROARYLPIPERAZINYL IMIDES AS 5-HT1A RECEPTOR LIGANDS AND POTENTIAL ANXIOLYTIC AGENTS - SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP STUDIES
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[4] NAN-190 - AN ARYLPIPERAZINE ANALOG THAT ANTAGONIZES THE STIMULUS EFFECTS OF THE 5-HT1A AGONIST 8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN (8-OH-DPAT)
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[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 154 (03) : 339 - 341
[5] N,N-DI-NORMAL-PROPYLSEROTONIN - BINDING AT SEROTONIN BINDING-SITES AND A COMPARISON WITH 8-HYDROXY-2-(DI-NORMAL-PROPYLAMINO)TETRALIN
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[6] SYNTHESIS AND EVALUATION OF NOVEL ALKYLPIPERAZINES AS POTENTIAL DOPAMINE ANTAGONISTS
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STEINSLAND, OS
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (06) : 678 - 683
[7] ARYLPIPERAZINE DERIVATIVES AS HIGH-AFFINITY 5-HT1A SEROTONIN LIGANDS
GLENNON, RA
NAIMAN, NA
LYON, RA
TITELER, M
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (10) : 1968 - 1971
[8] CENTRAL SEROTONIN RECEPTORS AS TARGETS FOR DRUG RESEARCH
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (01) : 1 - 12
[9] GLENNON RA, 1989, RECEPTOR PHARM FUNCT, P257
[10] HIBERT M, 1987, BRAIN 5 HT1A RECEPTO, P27

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