MICRO-OBSERVATION AND CHARACTERIZATION OF BONDING BETWEEN BONE AND HA-GLASS-TITANIUM FUNCTIONALLY GRADIENT COMPOSITE

被引:20
作者
MARUNO, S
ITOH, H
BAN, S
IWATA, H
ISHIKAWA, T
机构
[1] TOKYO KOUSEINENKIN HOSP,SHINJUKU KU,TOKYO 162,JAPAN
[2] AICHI GAKUIN UNIV,SCH DENT,CHIKUSA KU,NAGOYA 464,JAPAN
[3] NAGOYA UNIV,DEPT ORTHOPED SURG,SHOWA KU,NAGOYA,AICHI 466,JAPAN
关键词
HYDROXYAPATITE; TITANIUM; BONE;
D O I
10.1016/0142-9612(91)90204-N
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Bioactive composite implants consisting of hydroxyapatite (HA)-glass (G) ceramic layer and Ti-6Al-4V alloy, so-called HA-G-Ti functionally gradient implant, were provided for investigating the bonding behaviour of bone to the implant in vivo. The HA-G-Ti composites were implanted in femur and tibia of dog for various periods (1-12 month). Microstructural appearance of the interface between bone and the HA-G coating layer as well as the transverse sections of the HA-G coating layer and further apposition of bone to the implant have been studied in detail with SEM. The ingress of collagen fibres into the HA-G coating layer and the deposit of apatite on the collagen fibres and HA crystal grains being containing within the HA-G coating layer have been observed. Radiographical experiments indicate that the reparative process in the bone tissue surrounding the implants is markedly ahead even at one month after implantation. FT-IR measurement and X-ray diffraction were carried out for studying the characterization of the calcified bone matrix around the implants and the new bone proliferated along the HA-G-coated face (surface).
引用
收藏
页码:225 / 230
页数:6
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