TUMOR-NECROSIS-FACTOR IN SYNOVIAL-FLUID OF PATIENTS WITH TEMPOROMANDIBULAR DISORDERS

被引：82

作者：

FU, KY ^{[1
]}

MA, XC ^{[1
]}

ZHANG, ZK ^{[1
]}

CHEN, WF ^{[1
]}

机构：

[1] BEIJING MED UNIV,INST IMMUNOL,BEIJING 100081,PEOPLES R CHINA

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 1995年 / 53卷 / 04期

关键词：

D O I：

10.1016/0278-2391(95)90717-3

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Purpose: To assess tumor necrosis factor (TNF) activity in synovial fluid from patients with temporomandibular disorders. Patients and Methods: Tumor necrosis factor (TNF) activity in synovial fluid from 27 patients with temporomandibular disorders (TMDs) was studied using the MTT tetrazolium WEH1 164 clone 13 cell cytotoxicity assay. Results: No detectable TNF levels were found in five patients with a masticatory muscle disorder, but elevated TNF levels were found in 5 of 11 patients with TMJ disc displacement, and in 9 of 11 patients with degenerative joint disease. Conclusion: The findings of biologically active TNF in the synovial fluid of these patients suggests that it may play a role in the pathogenesis of certain temporomandibular disorders.

引用

页码：424 / 426

页数：3

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