ROLE OF PROLONGED EXCESSIVE ESTROGEN STIMULATION IN THE PATHOGENESIS OF ENDOMETRIAL SARCOMAS - 2 CASES AND A REVIEW OF THE LITERATURE

被引：22

作者：

ALTARAS, MM

JAFFE, R

COHEN, I

GRUBER, A

YANAIINBAR, I

BERNHEIM, J

机构：

[1] SAPIR MED CTR,DEPT PATHOL,KEFAR SAVA,ISRAEL

[2] SOROKA MED CTR,DEPT PATHOL,IL-84101 BEER SHEVA,ISRAEL

来源：

GYNECOLOGIC ONCOLOGY | 1990年 / 38卷 / 02期

关键词：

D O I：

10.1016/0090-8258(90)90054-O

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Two cases of endometrial sarcoma that developed many years after exposure to unopposed exogenous and endogenous estrogens, with no previous pelvic irradiation, are described. The literature is reviewed and the possible effect of prolonged unopposed estrogen stimulation is suggested as an etiologic factor in such extremely rare conditions. These cases add additional support to the assumption that prolonged and excessive endogenous or exogenous unopposed estrogen stimulation of the uterus may increase the risk of endometrial sarcoma. © 1990.

引用

页码：273 / 277

页数：5

共 16 条

[1] THECA AND GRANULOSA-CELL TUMORS AND ENDOMETRIAL ADENOCARCINOMA [J].