APPLICATION OF PHARMACOKINETICS AND BIOPHARMACEUTICS IN THE DESIGN OF TOXICOLOGICAL STUDIES

被引：13

作者：

SMYTH, RD

HOTTENDORF, GH

机构：

[1] BRISTOL MYERS CO LABS, DEPT PHARMACOKINET, SYRACUSE, NY 13201 USA

[2] BRISTOL MYERS CO LABS, DEPT TOXICOL, SYRACUSE, NY 13201 USA

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1980年 / 53卷 / 02期

关键词：

D O I：

10.1016/0041-008X(80)90418-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：179 / 195

页数：17

共 12 条

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BENET, LZ .

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[2] USE OF TC-99M LABELED TRIETHYLENETETRAMINE-POLYSTYRENE RESIN FOR MEASURING GASTRIC-EMPTYING RATE IN HUMANS [J].

DIGENIS, GA ;

BEIHN, RM ;

THEODORAKIS, MC ;

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[3]

HOTTENDORF GH, 1975, P EUR SOC TOXICOL, V17, P255

[4]

KAPLAN S A, 1972, Drug Metabolism Reviews, V1, P15, DOI 10.3109/03602537208993907

[5]

LUKAS G, 1971, J PHARMACOL EXP THER, V178, P562

[6] USE OF RABBITS FOR GI DRUG ABSORPTION STUDIES [J].

MAEDA, T ;

TAKENAKA, H ;

YAMAHIRA, Y ;

NOGUCHI, T .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1977, 66 (01) :69-73

[7] ORAL TOXICITY OF POLYETHYLENE-GLYCOL (PEG-200) IN MONKEYS AND RATS [J].

PRENTICE, DE ;

MAJEED, SK .

TOXICOLOGY LETTERS, 1978, 2 (02) :119-122

[8]

RITSCHEL WA, 1976, HDB PHARMACOKINETICS

[9] EFFECT OF METHYLCELLULOSE ON ABSORPTION OF NITROFURANTOIN FROM GASTROINTESTINAL TRACT [J].

SEAGER, H .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1968, 20 (12) :968-&

[10] EVALUATION OF THE AVAILABILITY OF DRUGS INCORPORATED IN RAT LABORATORY DIET [J].

SMYTH, RD ;

GAVER, RC ;

DANDEKAR, KA ;

VANHARKEN, DR ;

HOTTENDORF, GH .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1979, 50 (03) :493-499

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