MULTIPLE OVERLAPPING POSITIONS OF NUCLEOSOMES WITH SINGLE IN-VIVO ROTATIONAL SETTING IN THE HANSENULA-POLYMORPHA RNA-POLYMERASE-II MOX PROMOTER

被引：24

作者：

COSTANZO, G

DIMAURO, E

NEGRI, R

PEREIRA, G

HOLLENBERG, C

机构：

[1] UNIV ROMA LA SAPIENZA, DIPARTIMENTO GENET & BIOL MOLEC, FDN IST PASTEUR FDN CENCI BOLOGNETTI, I-00185 ROME, ITALY

[2] UNIV DUSSELDORF, INST MICROBIOL, D-40225 DUSSELDORF, GERMANY

来源：

JOURNAL OF BIOLOGICAL CHEMISTRY | 1995年 / 270卷 / 19期

关键词：

D O I：

10.1074/jbc.270.19.11091

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In vivo nucleotide level mapping of nucleosomes in the promoter of the methanol oxidase (MOX) gene in the yeast Hansenula polymorpha is reported. The 4 nucleosomes analyzed are organized in families; they localize in alternative positions along a unique rotational phase, and the linker regions can be occupied by alternative nucleosomes. This organization underscores a substantial freedom of choice by histone octamers when nucleating on a promoter region.

引用

页码：11091 / 11097

页数：7

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