EFFECT OF ESSENTIAL FATTY ACID-DEFICIENT DIET ON THE LEVELS OF PROSTAGLANDINS AND THEIR FATTY-ACID PRECURSORS IN THE RABBIT BRAIN

被引：25

作者：

HASSAM, AG

WILLIS, AL

DENTON, JP

STEVENS, P

CRAWFORD, MA

机构：

[1] Department of Biochemistry, Nuffield Laboratories of Comparative Medicine, Zoological Society of London, Regent's Park, London

来源：

LIPIDS | 1979年 / 14卷 / 01期

关键词：

D O I：

10.1007/BF02533572

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rabbits were maintained on an EFA-deficient diet. After eight weeks on this diet, lipid analysis showed no major alterations in the levels of brain dihomo-gamma-linolenic and arachidonic acids when compared with animals maintained on the standard laboratory diet. However, there were substantial reductions in the brain prostaglandin contents. It is suggested that the dihomo-gamma-linolenic acid and arachidonic acid utilized for prostaglandin production may be more directly related to the dietary essential fatty acid input rather than to the size of the precursor pool in the principal phospholipids. © 1979 American Oil Chemists' Society.

引用

页码：78 / 80

页数：3

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