TREATMENT OF DRUG-INDUCED AGRANULOCYTOSIS WITH RECOMBINANT GM-CSF

被引：29

作者：

PALMBLAD, J

JONSON, B

KANERUD, L

机构：

[1] SODER SJUKHUSET, DIV HEMATOL, S-10064 STOCKHOLM, SWEDEN

[2] SODER SJUKHUSET, DEPT MED 3, DIV RHEUMATOL, S-10064 STOCKHOLM, SWEDEN

来源：

JOURNAL OF INTERNAL MEDICINE | 1990年 / 228卷 / 05期

关键词：

agranulocytosis; growth factors;

D O I：

10.1111/j.1365-2796.1990.tb00275.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Abstract. A 53‐year male patient, treated for rheumatoid arthritis with sulphasalazine, developed a total agranulocytosis. When this state had prevailed for at least 10 d no bone marrow granulocyte progenitor cells were detectable. Intravenous GM‐CSF treatment was initiated 5 d later, and the patient recovered within the next 6 d. GM‐CSF treatment for severe agranulocytosis deserves further investigation. 1990 Blackwell Publishing Ltd

引用

页码：537 / 539

页数：3