DETERMINATION OF KETOPROFEN BY DIRECT INJECTION OF DEPROTEINIZED BODY-FLUIDS INTO A HIGH-PRESSURE LIQUID-CHROMATOGRAPHIC SYSTEM

被引：12

作者：

BALLERINI, R ^{[1
]}

CAMBI, A ^{[1
]}

DELSOLDATO, P ^{[1
]}

MELANI, F ^{[1
]}

MELI, A ^{[1
]}

机构：

[1] A MENARINI PHARMACEUT,VIA SETTE SANTI 1,I-50131 FLORENCE,ITALY

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1979年 / 68卷 / 03期

关键词：

Anti‐inflammatory agents—ketoprofen; high‐pressure liquid chromatographic analysis in various body fluids; High‐pressure liquid chromatography—analysis; ketoprofen in various body fluids; Ketoprofen—high‐pressure liquid chromatographic analysis in various body fluids;

D O I：

10.1002/jps.2600680330

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A rapid, sensitive, and specific determination of ketoprofen in human and animal deproteinized body fluids by reversed‐phase high‐pressure liquid chromatography is presented. The acid is detectable in amounts as low as 0.1 γg/ml. Limits of error are in the range of ±5.1% of the sample mean. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：366 / 368

页数：3