ANTIBIOTIC SCREENING OF MEDICINAL-PLANTS OF THE BRITISH-COLUMBIAN NATIVE PEOPLES

被引:158
作者
MCCUTCHEON, AR [1 ]
ELLIS, SM [1 ]
HANCOCK, REW [1 ]
TOWERS, GHN [1 ]
机构
[1] UNIV BRITISH COLUMBIA,DEPT MICROBIOL,VANCOUVER V6T 2B1,BC,CANADA
关键词
ANTIBIOTIC ACTIVITY; PSEUDOMONAS-AERUGINOSA; STAPHYLOCOCCUS-AUREUS; TRADITIONAL MEDICINES (BRITISH-COLUMBIA);
D O I
10.1016/0378-8741(92)90036-Q
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
One hundred methanolic plant extracts, 96 of which had documented medicinal uses by British Columbian native peoples, were screened for antibiotic activity against 11 bacterial strains. Eighty-five percent were found to have significant antibiotic activity against at least two of the bacteria tested. Ninety-five percent of the plants categorized as potential antibiotics based on their ethnobotanical usage were found to exhibit significant antibiotic activity. Seventy-five were found to be active against methicillin-resistant Staphylococcus aureus, 46 were active against an antibiotic supersusceptible strain of Pseudomonas aeruginosa and 18 of these were also active against a wild type strain. The extracts with the broadest spectra of activity were prepared from: Alnus rubra bark and catkins, Fragaria chiloensis leaves, Moneses uniflora aerial parts, and Rhus glabra branches.
引用
收藏
页码:213 / 223
页数:11
相关论文
共 6 条
[1]  
Erichsen-Brown C., 1989, MED OTHER USES N AM
[2]  
Lennette E.H., 1985, MANUAL CLIN MICROBIO, V4th, P978
[3]  
TURNER NJ, 1980, OCCASIONAL PAPERS SE
[4]  
TURNER NJ, 1975, BRIT COLUMBIA PROVIN, V34
[5]  
TURNER NJ, 1990, BRIT COLUMBIA PROVIN, V25
[6]  
TURNER NJ, 1978, BRIT COLUMBIA PROVIN, V36