Human papillomavirus detection in high-grade squamous intraepithelial lesions - Comparison of hybrid capture assay with a polymerase chain reaction system

被引：10

作者：

Nindl, I ^{[1
]}

Zahm, DM ^{[1
]}

Meijer, CJLM ^{[1
]}

Walboomers, JMM ^{[1
]}

Schneider, A ^{[1
]}

机构：

[1] FREE UNIV AMSTERDAM HOSP,DEPT PATHOL,SECT MOLEC PATHOL,AMSTERDAM,NETHERLANDS

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 1995年 / 23卷 / 04期

关键词：

D O I：

10.1016/0732-8893(95)00187-5

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The validity of human papillomavirus (HPV) detection using the hybrid capture assay (HCA) was compared with the polymerase chain reaction (PCR) in 38 patients with high-grade squamous intraepithelial lesions (HSILs). HCA and PCR showed 84% agreement for HPV detection. HCA missed a significant higher proportion of HSIL compared with PCR (21% vs. 5%; P = .04). Thus, the sensitivity of HCA should be increased before this test can be recommended for HSIL.

引用

页码：161 / 164

页数：4

共 16 条

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