H-3 URIDINE UPTAKE IN HUMAN LEUKEMIA HL-60 CELLS EXPOSED TO EXTREMELY LOW-FREQUENCY ELECTROMAGNETIC-FIELDS

被引:7
作者
AZADNIV, M
MILLER, MW
机构
[1] Department of Biophysics, School of Medicine, Dentistry The University of Rochester, Rochester
关键词
D O I
10.1016/0006-291X(92)91577-D
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Human leukemia HL-60 cells in vitro were exposed or sham-exposed to a 60 Hz electric (3.40 mV/m) or magnetic 10 G (1 μT) field for 5 hr in an attempt to replicate the results of a previously published report (1) of increased uptake of [3H] uridine in response to similar exposure conditions. The results of the present experiments indicated no treatment effect of the fields on the uridine incorporation. The ability to detect differences in [3H] uridine uptake were confirmed in a negative control experiment. A 'negative control' experiment demonstrated a statistically significant increase in 3H-uridine uptake for cells at 37 °C relative to those at 4 °C. © 1992.
引用
收藏
页码:437 / 444
页数:8
相关论文
共 4 条
[1]  
BASSEN H, 1992, BIOELECTROMAGNETICS, V136, P183
[2]  
CARSTENSEN EL, 1987, BIOL EFFECTS TRANSMI, P397
[3]   DELINEATION OF ELECTRIC AND MAGNETIC-FIELD EFFECTS OF EXTREMELY LOW-FREQUENCY ELECTROMAGNETIC-RADIATION ON TRANSCRIPTION [J].
GREENE, JJ ;
SKOWRONSKI, WJ ;
MULLINS, JM ;
NARDONE, RM ;
PENAFIEL, M ;
MEISTER, R .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 174 (02) :742-749
[4]  
SHEPPARD AR, 1977, BIOL EFFECTS ELECTRI