HUMAN MICRONUCLEUS COUNTS ARE CORRELATED WITH AGE, SMOKING, AND CESIUM-137 DOSE IN THE GOIANIA (BRAZIL) RADIOLOGICAL ACCIDENT

被引:63
作者
DACRUZ, AD
MCARTHUR, AG
SILVA, CC
CURADO, MP
GLICKMAN, BW
机构
[1] UNIV VICTORIA,CTR ENVIRONM HLTH,VICTORIA V8W 2Y2,BC,CANADA
[2] UNIV VICTORIA,DEPT BIOL,VICTORIA V8W 2Y2,BC,CANADA
[3] LEIDE NEVES FERREIRA FDN,CYTOGENET LAB,GOIANIA,BRAZIL
[4] CATHOLIC UNIV GOIAS,DEPT BIOL,GOIANIA,BRAZIL
来源
MUTATION RESEARCH-ENVIRONMENTAL MUTAGENESIS AND RELATED SUBJECTS | 1994年 / 313卷 / 01期
基金
加拿大自然科学与工程研究理事会;
关键词
MICRONUCLEI; CESIUM-1S7; GOIANIA RADIOLOGICAL ACCIDENT; ENVIRONMENTAL MUTAGENESIS; HUMAN POPULATIONS;
D O I
10.1016/0165-1161(94)90033-7
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
A random sample of 276 people representing control, direct exposure, and probable indirect exposure in the Goiania, Brazil radiological accident was examined using micronuclei as indicators of cytogenetic damage. The Goiania subjects were analyzed for interactions of age, lifestyle, and ionizing radiation dose. Increases in micronucleus frequencies were most strongly correlated with the dose of ionizing radiation, but age, alcohol consumption, and smoking habits also affected micronucleus frequencies. Despite these additional influences, micronucleus frequencies can be useful as biological dosimeters.
引用
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页码:57 / 68
页数:12
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