PREDICTING PROTEIN DIFFUSION-COEFFICIENTS

被引:159
作者
BRUNE, D
KIM, S
机构
[1] Department of Chemical Engineering, University of Wisconsin, Madison
关键词
LINEAR OPERATOR THEORY; FREDHOLM THEOREMS;
D O I
10.1073/pnas.90.9.3835
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Diffusion coefficients for proteins in water are predicted. The numerical method developed is general enough to be applied to a wide range of protein surface shapes, from rodlike to globular. Results are presented for lysozyme and tobacco mosaic virus, and they are compared with actual data and with predictions made by less general methods.
引用
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页码:3835 / 3839
页数:5
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