PROTON AND DEUTERON SPIN TARGETS IN BIOLOGICAL STRUCTURE RESEARCH

被引：50

作者：

STUHRMANN, HB ^{[1
]}

BURKHARDT, N ^{[1
]}

DIETRICH, G ^{[1
]}

JUNEMANN, R ^{[1
]}

MEERWINCK, W ^{[1
]}

SCHMITT, M ^{[1
]}

WADZACK, J ^{[1
]}

WILLUMEIT, R ^{[1
]}

ZHAO, J ^{[1
]}

NIERHAUS, KH ^{[1
]}

机构：

[1] MAX PLANCK INST MOLEC GENET,D-14195 BERLIN,GERMANY

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 1995年 / 356卷 / 01期

关键词：

D O I：

10.1016/0168-9002(94)01461-2

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Polarized neutron scattering from polarized nuclear spin targets has been used to study the in situ structure of ribosomal components in solutions. The progress of this technique is substantiated by first results obtained from protonated tRNA and mRNA labels in a deuterated ribosome. The site of the tRNA could be determined uniquely, whereas there are several orientations of the [tRNA](2)-mRNA complex which are compatible with the neutron scattering data. Similarly, a small, protonated mRNA fragment was studied. Its size favours a complicated path of the mRNA chain through the ribosome. The role of deuteron spin targets is discussed.

引用

页码：124 / 132

页数：9

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