EFFICIENT ONE-POT CONVERSION OF 6-METHYL-2-NITROANILINE INTO 1-ALKYLOXY-2-ALKYL-4-METHYL, 1-BENZYLOXY-2-PHENYL-4-METHYL, AND 1-ALLYLOXY-4-METHYL-2-VINYL-BENZIMIDAZOLE

被引：9

作者：

GARDINER, JM

LOYNS, CR

机构：

[1] Department of Chemistry, University of Manchester Institute of Science and Technology UMIST, Manchester M60 1QD

来源：

SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 06期

关键词：

D O I：

10.1080/00397919508013418

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

6-Methyl-2-nitroaniline reacts with alkyl, benzyl and allyl halides and NaH as base, to afford 1-alkoxy-2-alkyl-, 1-benzyloxy-2-aryl- and 1-allyloxy-2-vinyl-benzimidazoles in good to excellent yields (73-98%), via a novel one-pot N-alkylation-heterocyclization-O-alkylation sequence.

引用

页码：819 / 827

页数：9

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