PUTATIVE LEISHMANIA HYBRIDS IN THE EASTERN ANDEAN VALLEY OF HUANUCO, PERU

被引：80

作者：

DUJARDIN, JC

BANULS, AL

LLANOSCUENTAS, A

ALVAREZ, E

DEDONCKER, S

JACQUET, D

LERAY, D

AREVALO, J

TIBAYRENC, M

机构：

[1] ORSTOM,CNRS,UMR 9926,F-34032 MONTPELLIER,FRANCE

[2] UNIV PERUANA CAYETANO HEREDIA,INST MED TROP ALEXANDER VON HUMBOLDT,LIMA,PERU

来源：

ACTA TROPICA | 1995年 / 59卷 / 04期

关键词：

LEISHMANIA BRAZILIENSIS; L-PERUVIANA; EPIDEMIC; RECOMBINATION; ENZYME ELECTROPHORESIS; RAPD; MOLECULAR KARYOTYPE;

D O I：

10.1016/0001-706X(95)00094-U

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

During an outbreak of tegumentary leishmaniasis that developed in the 1990s in the Eastern Andean valley of Huanuco, Peru, the coexistence of Andean (uta) and sylvatic leishmaniases was suspected for ecological and geographical reasons, and sympatric sampling was carried out. Seven human isolates of Leishmania were characterized by multilocus enzyme electrophoresis, random amplification of polymorphic DNA and molecular karyotyping. The three methods identified 3 isolates as L. braziliensis, and 4 isolates as putative hybrids with characters of L. braziliensis and L. peruviana. Data from Huanuco are compared to previous results from other areas endemic for uta. Biological and epidemiological implications are discussed.

引用

页码：293 / 307

页数：15

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