SERUM INTERLEUKIN-2-RECEPTOR LEVELS IN UVEITIS

被引：30

作者：

AROCKERMETTINGER, E ^{[1
]}

ASENBAUER, T ^{[1
]}

ULBRICH, S ^{[1
]}

GRABNER, G ^{[1
]}

机构：

[1] KRANKENHAUS MODLING,MODLING,AUSTRIA

来源：

CURRENT EYE RESEARCH | 1990年 / 9卷

关键词：

D O I：

10.3109/02713689008999415

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

This study reports on serum interleukin 2-receptor (IL-2R) levels in uveitis patients. IL-2R is the mediator protein of interleukin 2 (IL-2), a mitogenetic cytokine of primarily immune cell interaction. Stimulated T-cells readily express IL-2R on their cell surface and release a soluble form into serum. The measurement of IL-2R serum levels was performed using a monoclonal antibody based ELISA with age and sex matched healthy blood donors serving as the control group. The increase of IL-2R serum levels in patients affected by heterochromic cyclitis Fuchs (HCF) and a small group of children with chronic anterior uveitis affected by juvenile rheumatoid arthritis (JRA) was statistically highly significant, when compared to the control group (n=84, α=0.01). Serum levels of patients with intermediate uveitis (IU), patients with HLA-B27 positive acute anterior uveitis (AAU) and patients with HLA-B27 negative AAU did not differ significantly from the controls. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：25 / 29

页数：5

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